Strychnine-sensitive and -insensitive Inhibitions in Cat's Retina

نویسندگان

چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Strychnine-sensitive and -insensitive inhibitions in the cat's retina.

Effects of strychnine on intraretinal inhibition were investigated by recording unitary discharges from the optic tract fibers. Units were classed as on, off and on off according to their discharge patterns in response to diffuse illumination of the retina. Strychnine enhanced the firing rate of spontaneous discharge in the dark. ' On' inhibition of an off unit was greatly suppressed by strychn...

متن کامل

Strychnine-sensitive glycine receptors depress hyperexcitability in rat dentate gyrus.

Previously we have shown that strychnine-sensitive glycine-gated chloride channels (GlyRs) are functionally expressed by CA1 pyramidal cells and GABAergic interneurons in mature rat hippocampal slices. We now report that glycine application to dentate granule cells and hilar interneurons recorded in acute slices from adolescent rats elicits a strychnine-sensitive current similar to glycine-medi...

متن کامل

Myocardial ischemia recruits mechanically insensitive cardiac sympathetic afferents in cats.

Chest pain caused by myocardial ischemia is mediated by cardiac sympathetic afferents. Although silent nociceptors exist in somatic structures and some visceral organs, their presence in the heart remains uncertain. The present study examined the presence and the functional characteristics of mechanically insensitive cardiac sympathetic afferents using an electrical search technique. Single-uni...

متن کامل

Effects of strychnine-insensitive glycine receptor ligands in rats discriminating dizocilpine or phencyclidine from saline.

Several pharmacologically distinct sites are known to modulate the N-methyl-D-aspartate (NMDA) receptor/ion complex, including a site within the ion channel which binds uncompetitive antagonists like phencyclidine (PCP) or dizocilpine. Glycine acts as a co-agonist for activation of the NMDA receptor complex through a strychnine-insensitive receptor, which is a potential target for novel therape...

متن کامل

The effect of strychnine, bicuculline, and picrotoxin on X and Y cells in the cat retina

The effect of intravenous strychnine and the GABA antagonists picrotoxin and bicuculline upon the discharge pattern of center-surround-organized cat retinal ganglion cells of X and Y type were studied. Stimuli (mostly scotopic, and some photopic) were selected such that responses from both on and off-center cells were either due to the center, due to the surround, or clearly mixed. Pre-drug con...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: The Tohoku Journal of Experimental Medicine

سال: 1968

ISSN: 0040-8727,1349-3329

DOI: 10.1620/tjem.96.37